How Long Does Oxycodone Stay In Your System?

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How Long Does Oxycodone Stay In Your System?

Oxycodone is a powerful prescription pain reliever that can be detected in the body up to four days after the last dose. Some people who use oxycodone long-term may have traces of this drug in their bodies for more extended periods. If you or someone you love is struggling with oxycodone abuse or addiction, contact Vertava Health of Ohio today to learn about our drug treatment programs.


Oxycodone is a powerful prescription pain reliever, and it is the active ingredient the most widely abused prescription painkillers in the country. Oxycodone is a class of opioids that are used for pain relief but can also lead to extreme physical dependence in the body and have addictive effects.

Oxycodone can typically be detected in a person’s system for up to four days, but this number can vary depending on personal factors. These factors include age, metabolism, duration of use, and the amount of drug ingested.

If you or someone you know is struggling with Oxycodone addiction, help is available. Vertava Health of Ohio is one of the many treatment facilities that provide addiction programs to help individuals overcome prescription drug abuse.

What Is Oxycodone?

Oxycodone is a drug used to relieve moderate to severe pain and is classified as an opioid (narcotic). These drugs change how your body feels and responds to pain. Oxycodone can come in a variety of forms, from rapid release to extended-release tablets.

Percocet and Percodan are rapid-relief forms of oxycodone and can be taken every six hours for pain. Oxycontin is an extended-release form and provides a 12-hour window of pain relief.

The extended-release Oxycontin pills have become one of the leading drugs in the current opioid addiction crisis. People crush up or inject these forms of oxycodone for the fast-acting and euphoric effects they can provide.

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Oxycodone Detection Times

Oxycodone is typically detectable in a person’s system for up to four days after use. However, this number can be longer depending on the frequency and dosage taken. If large amounts of oxycodone were ingested, traces of the drug will most likely be detectable in the body for a longer period of time.

Knowing how long traces of oxycodone are within the system can be beneficial for a variety of reasons. This type of identification can help determine when to be on the lookout for withdrawal symptoms or to identify when and for how long oxycodone will show up on a drug test.

Oxycodone can be detected in a person’s system long after the effects of the drug end. The detection window for oxycodone depends on a variety of factors, including the type of test used.

The following are common tests used and the amount of time each test can typically detect oxycodone in the system:

Urine Tests

If a person is screened via a urine sample, oxycodone could be detected for up to four days. Urine tests are the most common type of drug screening for opiates. These types of tests are most often used by employers and court systems.

Blood Tests

Oxycodone can show up in a person’s blood for at least 24 hours after the initial dose. While these tests are not conducted as much as urine tests, the blood is a very reliable source to show traces of the drug.

How Is Oxycodone Metabolized?

After ingestion, oxycodone is processed through the digestive system and is broken down in the liver. The kidneys process the drug through the urine, and the body may excrete trace amounts through sweat.

The half-life of oxycodone is approximately three to six hours. This means that after up to six hours, the body has processed over half of the oxycodone dose out of the body. Typically the drug is processed entirely out of the body in 20 to 24 hours, as the entire metabolic process can take longer.

Factors That Influence How Oxycodone Is Metabolized

Several personal factors can affect how long Oxycodone remains in a person’s system. These factors include a person’s age, weight, and dietary habits.


Older individuals tend to experience longer windows of detection times. This is because older people have slower metabolisms and work harder at processing the drug. Younger people have faster metabolisms, and their bodies can breakdown the drug at a quicker rate. Typically, a young person will have a shorter oxycodone detection window than their elder counterparts.


A person with a high body fat ratio may retain oxycodone for longer periods of time. Likewise, a person who has a more moderate fat ratio will flush oxycodone quicker.

Dietary Habits

Taking oxycodone on an empty stomach could result in shorter detection time, as opposed to taking the drug with a meal that is high in fat. Hydration is also an essential factor in detection time. The more water someone drinks, the faster his or her body can process the drug.

Oxycodone Addiction Treatment Services At Vertava Health of Ohio

At Vertava Health of Ohio, we understand that facing an opioid addiction can be difficult. If you are abusing or addicted to oxycodone, our treatment specialists can offer a compassionate and personalized approach to help you face and overcome your addiction.

Recovery from oxycodone abuse is not simple, but it is possible with the right treatment. At Vertava Health of Ohio, we offer specialized drug addiction treatment programs that integrate quality medical care with a variety of other therapeutic and effective treatment services.

Our treatment services include:

  • medical detox services
  • individual counseling
  • medication-assisted treatment (MAT)
  • group therapy
  • holistic and alternative therapies

Based in a state with one of the highest rates of fatal opioid overdoses in the country, our Ohio treatment specialists understand the devastation opioid addiction can have on a person and their loved ones.

If you or someone you know is struggling with opioid abuse, contact Vertava Health of Ohio through our free and confidential helpline today.


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